3000-75-7
3000-75-7
Chemical Structure
nAChR-IN-2
- CAS 番号: 3000-75-7
- Formula:C8H12N2
- Molecular Weight:136.19
IUPAC Name: N-(pyridin-3-ylmethyl)ethanamine
InChIKey: SGROJTFSHJVVSF-UHFFFAOYSA-N
SMILES: CCNCC1=CC=CN=C1
Biological Activity: nAChR-IN-2 (Compound 2) is an inhibitor of insect nicotinic acetylcholine receptors (nAChR). nAChR-IN-2 inhibits the binding of α-bungarotoxin (HY-P1264) to the ACh site of insect nAChR in honeybee heads, with an IC50 of 360 μM. nAChR-IN-2 also inhibits the binding of Phencyclidine to the NCB/PCP site of insect nAChR in honeybee heads, with an IC50 of 84 μM[1].
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nAChR-IN-2 | nAChR-IN-2 (Compound 2) is an inhibitor of insect nicotinic acetylcholine receptors (nAChR). nAChR-IN-2 inhibits the binding of α-bungarotoxin (HY-P1264) to the ACh site of insect nAChR in honeybee heads, with an IC50 of 360 μM. nAChR-IN-2 also inhibits the binding of Phencyclidine to the NCB/PCP site of insect nAChR in honeybee heads, with an IC50 of 84 μM. | |||||||||||||||||||||
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References
Keywords
