3052736-45-2

COX-2/15-LOX-IN-4 Chemical Structure
3052736-45-2

Chemical Structure

COX-2/15-LOX-IN-4

  • CAS No.: 3052736-45-2
  • Formula:C23H20FN3OS
  • Molecular Weight:405.49

InChIKey: NBGCIRJUCBFWMT-UHFFFAOYSA-N

SMILES: COC(C=C1)=CC=C1C2=NC3=C(C(CCCC4)=C4S3)C(NC5=CC=C(F)C=C5)=N2

Biological Activity: COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor of COX-2/15-LOX with IC50s of 0.075 μM and 1.97 μM, respectively. COX-2/15-LOX-IN-4 can inhibit LPS-induced cell production of promoting cytokines (IL-6, ROS) with specific anti-inflammatory activity[1].

Cat. No. Product Name Purity Description Pricing
HY-155161 		COX-2/15-LOX-IN-4 COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor of COX-2/15-LOX with IC50s of 0.075 μM and 1.97 μM, respectively. COX-2/15-LOX-IN-4 can inhibit LPS-induced cell production of promoting cytokines (IL-6, ROS) with specific anti-inflammatory activity.
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