3064305-88-7
3064305-88-7
Chemical Structure
AA-17010
- CAS No.: 3064305-88-7
- Formula:C19H22N4O4
- Molecular Weight:370.40
InChIKey: DHHDVLBFEMPOJB-UHFFFAOYSA-N
SMILES: O=C(C(N(C(N(C)C1=C2)=O)C1=CC3=C2C4(CCNCC4)CO3)CC5)NC5=O
Biological Activity: AA-17010 is a Cereblon ligand with an IC50 of 0.20 μM and a Ki of 0.08 μM. AA-17010 serves as an E3 ligase ligand for the synthesis of PROTAC KRAS degraders, such as CW-10201 (HY-189305)[1].
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AA-17010 | AA-17010 is a Cereblon ligand with an IC50 of 0.20 μM and a Ki of 0.08 μM. AA-17010 serves as an E3 ligase ligand for the synthesis of PROTAC KRAS degraders, such as CW-10201 (HY-189305). | |||||||||||||||||||||
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