353234-67-0
353234-67-0
Chemical Structure
2,2,2-TEMPS
- CAS No.: 353234-67-0
- Formula:C19H23F3N2O3S
- Molecular Weight:416.46
InChIKey: ICFXZBZASBXILF-UHFFFAOYSA-N
SMILES: O=S(N(CC1=CC=CN=C1)C2=CC(OC(CCC)C)=CC=C2)(CC(F)(F)F)=O
Biological Activity: 2,2,2-TEMPS is a mGlu2 receptor positive allosteric modulator (EC50 = 14 nM). 2,2,2-TEMPS can be used in research on psychiatric disorders[1][2].
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2,2,2-TEMPS | 2,2,2-TEMPS is a mGlu2 receptor positive allosteric modulator (EC50 = 14 nM). 2,2,2-TEMPS can be used in research on psychiatric disorders. | |||||||||||||||||||||
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References
- [1]. Cid JM, et al. Metabotropic glutamate receptor 2 activators. InSmall molecule therapeutics for schizophrenia 2014 Apr 16 (pp. 101-142). Cham: Springer International Publishing.
- [2]. Lundström L, et al. Pharmacological and molecular characterization of the positive allosteric modulators of metabotropic glutamate receptor 2. Neuropharmacology. 2016 Dec;111:253-265.
