35554-44-0
Chemical Structure
Imazalil
Synonym(s): Enilconazole
- CAS No.: 35554-44-0
- Formula:C14H14Cl2N2O
- Molecular Weight:297.18
IUPAC Name: 1-(2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
InChIKey: PZBPKYOVPCNPJY-UHFFFAOYSA-N
SMILES: C=CCOC(C1=CC=C(Cl)C=C1Cl)CN2C=CN=C2
Biological Activity: Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Imazalil | 99.54% | Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder. | ||||||||||||||||||||
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Imazalil (Standard) | ≥98% | Imazalil (Standard) is the analytical standard of Imazalil. This product is intended for research and analytical applications. Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder. | ||||||||||||||||||||
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- [1]. Hiroyuki Kojima, et al. Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):338-45. [Content Brief]
- [2]. Shohei Yoshimaru, et al. Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR. J Toxicol Sci. 2018;43(7):443-450. [Content Brief]
- [3]. Cuiyuan Jin, et al. Chronic exposure of mice to low doses of imazalil induces hepatotoxicity at the physiological, biochemical, and transcriptomic levels. Environ Toxicol. 2018 Jun;33(6):650-658. [Content Brief]
Keywords
