380192-76-7
380192-76-7
Chemical Structure
PRMT5-IN-46
- CAS No.: 380192-76-7
- Formula:C19H22ClNO2
- Molecular Weight:331.84
IUPAC Name: 1-((4-chlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol
InChIKey: XFPRVFPKQLFJBJ-UHFFFAOYSA-N
SMILES: ClC1=CC=C(COCC(CN2CC3=C(CC2)C=CC=C3)O)C=C1
Biological Activity: PRMT5-IN-46 (compound 278) inhibits PRMT5 with IC50s of 1-10 μM. PRMT5 is a methyltransferase which is associated with specific genetic alterations. PRMT5-IN-46 can be used for research of proliferative diseases, metabolic disorders, and blood diseases[1].
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PRMT5-IN-46 | PRMT5-IN-46 (compound 278) inhibits PRMT5 with IC50s of 1-10 μM. PRMT5 is a methyltransferase which is associated with specific genetic alterations. PRMT5-IN-46 can be used for research of proliferative diseases, metabolic disorders, and blood diseases. | |||||||||||||||||||||
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References
Keywords
