5096-70-8
Chemical Structure
(-)-N-methylcoclaurine
Synonym(s): (–)-(1R)-N-methylcoclaurine
- CAS No.: 5096-70-8
- Formula:C18H21NO3
- Molecular Weight:299.36
IUPAC Name: (R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol
InChIKey: BOKVLBSSPUTWLV-MRXNPFEDSA-N
SMILES: OC1=CC2=C(C=C1OC)CCN(C)[C@@H]2CC3=CC=C(O)C=C3
Biological Activity: (-)-N-methylcoclaurine ((-)-(1R)-N-methylcoclaurine) is a benzylisoquinoline alkaloid and melanogenesis inhibitor with an IC50 of 6.5 μM that can be found in the flower buds of Nelumbo nucifera. (-)-N-methylcoclaurine inhibits theophylline-stimulated melanogenesis in melanoma cells. (-)-N-methylcoclaurine can be used for the research of skin hyperpigmentation disorders[1].
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(-)-N-methylcoclaurine | (-)-N-methylcoclaurine ((-)-(1R)-N-methylcoclaurine) is a benzylisoquinoline alkaloid and melanogenesis inhibitor with an IC50 of 6.5 μM that can be found in the flower buds of Nelumbo nucifera. (-)-N-methylcoclaurine inhibits theophylline-stimulated melanogenesis in melanoma cells. (-)-N-methylcoclaurine can be used for the research of skin hyperpigmentation disorders. | |||||||||||||||||||||
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