545434-89-7
Chemical Structure
Petrobactin
- CAS No.: 545434-89-7
- Formula:C34H50N6O11
- Molecular Weight:718.79
InChIKey: GKIMOVAPSAVJHZ-UHFFFAOYSA-N
SMILES: O=C(C(CC(NCCCCNCCCNC(C1=CC=C(C(O)=C1)O)=O)=O)(CC(NCCCCNCCCNC(C2=CC=C(C(O)=C2)O)=O)=O)O)O
Biological Activity: Petrobactin is a bis-catechol α-hydroxy acid siderophore, Fe (III) chelator, and oxidative stress protector. Petrobactin is produced by marine bacteria and Bacillus anthracis Sterne strain under iron-starvation conditions. Petrobactin promotes the biodegradation of petroleum hydrocarbons by microorganisms, as well as the proliferation, virulence exertion, vegetative growth, sporulation efficiency, and spore binding of Bacillus anthracis; it also mediates community iron acquisition in the global ocean. Petrobactin can be used in anthrax-related research[1][2][3][4].
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Petrobactin | Petrobactin is a bis-catechol α-hydroxy acid siderophore, Fe (III) chelator, and oxidative stress protector. Petrobactin is produced by marine bacteria and Bacillus anthracis Sterne strain under iron-starvation conditions. Petrobactin promotes the biodegradation of petroleum hydrocarbons by microorganisms, as well as the proliferation, virulence exertion, vegetative growth, sporulation efficiency, and spore binding of Bacillus anthracis; it also mediates community iron acquisition in the global ocean. Petrobactin can be used in anthrax-related research. | |||||||||||||||||||||
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- [1]. Barbeau K, et al. Petrobactin, a photoreactive siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. Journal of the American Chemical Society. 2002 Jan 23;124(3):378-9. [Content Brief]
- [2]. Koppisch AT, et al. Petrobactin is the primary siderophore synthesized by Bacillus anthracis str. Sterne under conditions of iron starvation. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2005 Dec;18(6):577-85. [Content Brief]
- [3]. Hagan AK, et al. Petrobactin Protects against Oxidative Stress and Enhances Sporulation Efficiency in Bacillus anthracis Sterne. mBio. 2018 Nov 06;9(6):e02079-18.
- [4]. Manck LE, et al. Petrobactin, a siderophore produced by Alteromonas, mediates community iron acquisition in the global ocean. The ISME journal. 2022 Feb;16(2):358-369.
Keywords
