Petrobactin, a photoreactive siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus

  • J Am Chem Soc. 2002 Jan 23;124(3):378-9. doi: 10.1021/ja0119088.
Katherine Barbeau  1 ,  Guangping Zhang ,  David H Live ,  Alison Butler
Affiliations
  • 1. Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.
PMID: 11792199 DOI: 10.1021/ja0119088
Abstract

Petrobactin is a bis-catecholate, alpha-hydroxy acid siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. The Fe(III)-complexed form of petrobactin is photoreactive in natural sunlight, mediated by the Fe(III)-citrate moiety. The reaction results in decarboxylation of the petrobactin ligand and reduction of Fe(III) to Fe(II). This report is one of the first to show the photoreactivity of Fe(III)-siderophores mediated by the ferric ion-alpha-hydroxy acid group. The demonstration of light-mediated decarboxylation of an Fe(III)-siderophore complex raises questions about a possible functional role for photoreactivity in siderophore-mediated iron uptake.

Products