609-15-4
Chemical Structure
Ethyl 2-chloroacetoacetate
Synonym(s): A 21960
- CAS No.: 609-15-4
- Formula:C6H9ClO3
- Molecular Weight:164.59
IUPAC Name: ethyl 2-chloro-3-oxobutanoate
InChIKey: RDULEYWUGKOCMR-UHFFFAOYSA-N
SMILES: O=C(C(C(C)=O)Cl)OCC
Biological Activity: Ethyl 2-chloroacetoacetate (A 21960) is a Tn3 resolvase inhibitor, and inhibit synapse formation between resolvase and two directly repeated res sites. Ethyl 2-chloroacetoacetate is commonly used in in vitro enzymatic experiments. Ethyl 2-chloroacetoacetate inhibits the dehalogenation reaction by consuming intracellular GSH in yeast cells[1][2].
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Ethyl 2-chloroacetoacetate | 97.47% | Ethyl 2-chloroacetoacetate (A 21960) is a Tn3 resolvase inhibitor, and inhibit synapse formation between resolvase and two directly repeated res sites. Ethyl 2-chloroacetoacetate is commonly used in in vitro enzymatic experiments. Ethyl 2-chloroacetoacetate inhibits the dehalogenation reaction by consuming intracellular GSH in yeast cells. | ||||||||||||||||||||
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- [1]. Flanagan PM, et al. Analysis of inhibitors of the site-specific recombination reaction mediated by Tn3 resolvase. J Mol Biol. 1989;206(2):295-304. [Content Brief]
- [2]. Jörg G, et al. Fungal aerobic reductive dechlorination of ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae: mechanism of a novel type of microbial dehalogenation. Chembiochem. 2004 Jan 3;5(1):87-92. [Content Brief]
Keywords