Ethyl 2-chloroacetoacetate
Based on 1 Customer Validation
Ethyl 2-chloroacetoacetate (A 21960) is a Tn3 resolvase inhibitor, and inhibit synapse formation between resolvase and two directly repeated res sites. Ethyl 2-chloroacetoacetate is commonly used in in vitro enzymatic experiments. Ethyl 2-chloroacetoacetate inhibits the dehalogenation reaction by consuming intracellular GSH in yeast cells.
For research use only. We do not sell to patients.
- Purity: 97.47%
- CAS No.: 609-15-4
- Formula: C6H9ClO3
- Molecular Weight:164.59
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 609-15-4
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Appearance Liquid (Density: 1.172 g/cm³)
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Molecular Weight 164.59
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Formula C6H9ClO3
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Color Colorless to light yellow
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SMILES
O=C(C(C(C)=O)Cl)OCC
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Synonyms
A 21960
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (607.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (759 KB)
- English - EN (759 KB)
- Français - FR (759 KB)
- Deutsch - DE (759 KB)
- Norwegian - NO (759 KB)
- Español - ES (759 KB)
- Swedish - SV (759 KB)
- Italian - IT (759 KB)
- Korean - KR (759 KB)
- Portuguese - PT (759 KB)
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Handling Instructions (2659 KB)
References
[1]. Flanagan PM, et al. Analysis of inhibitors of the site-specific recombination reaction mediated by Tn3 resolvase. J Mol Biol. 1989;206(2):295-304. [Content Brief]
[2]. Jörg G, et al. Fungal aerobic reductive dechlorination of ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae: mechanism of a novel type of microbial dehalogenation. Chembiochem. 2004 Jan 3;5(1):87-92. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0757 mL | 30.3785 mL | 60.7570 mL | 151.8926 mL |
| 5 mM | 1.2151 mL | 6.0757 mL | 12.1514 mL | 30.3785 mL | |
| 10 mM | 0.6076 mL | 3.0379 mL | 6.0757 mL | 15.1893 mL | |
| 15 mM | 0.4050 mL | 2.0252 mL | 4.0505 mL | 10.1262 mL | |
| 20 mM | 0.3038 mL | 1.5189 mL | 3.0379 mL | 7.5946 mL | |
| 25 mM | 0.2430 mL | 1.2151 mL | 2.4303 mL | 6.0757 mL | |
| 30 mM | 0.2025 mL | 1.0126 mL | 2.0252 mL | 5.0631 mL | |
| 40 mM | 0.1519 mL | 0.7595 mL | 1.5189 mL | 3.7973 mL | |
| 50 mM | 0.1215 mL | 0.6076 mL | 1.2151 mL | 3.0379 mL | |
| 60 mM | 0.1013 mL | 0.5063 mL | 1.0126 mL | 2.5315 mL | |
| 80 mM | 0.0759 mL | 0.3797 mL | 0.7595 mL | 1.8987 mL | |
| 100 mM | 0.0608 mL | 0.3038 mL | 0.6076 mL | 1.5189 mL |
Ethyl 2-chloroacetoacetate Related Classifications
HY-Y0364 Related Classifications
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