73644-58-3
73644-58-3
Chemical Structure
TRH-βNA
- CAS No.: 73644-58-3
- Formula:C26H28N6O4
- Molecular Weight:488.54
InChIKey: SFXFXCFKKPUNMP-FKBYEOEOSA-N
SMILES: O=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(NC4=CC5=C(C=CC=C5)C=C4)=O)=O
Biological Activity: TRH-βNA is a substrate for determining the membrane TRH-deamidating enzyme (TRH-DE) activity and membrane pyroglutamyl aminopeptidase II (PPII) activity[1][2].
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TRH-βNA | TRH-βNA is a substrate for determining the membrane TRH-deamidating enzyme (TRH-DE) activity and membrane pyroglutamyl aminopeptidase II (PPII) activity. | |||||||||||||||||||||
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References
- [1]. Müller-Fielitz H, et al. Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis. Nat Commun. 2017 Sep 7;8(1):484. [Content Brief]
- [2]. Alvarez-Salas E, et al. Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II. Endocrinology. 2012 Aug;153(8):4067-76. [Content Brief]
Keywords
