744-80-9
744-80-9
Chemical Structure
Benzobarbital
- CAS No.: 744-80-9
- Formula:C19H16N2O4
- Molecular Weight:336.34
IUPAC Name: 1-benzoyl-5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
InChIKey: QMOWPJIFTHVQMB-UHFFFAOYSA-N
SMILES: O=C1NC(C(C2=CC=CC=C2)(CC)C(N1C(C3=CC=CC=C3)=O)=O)=O
Biological Activity: Benzobarbital is an active low-toxicity inductor of the liver monooxygenase system. Benzobarbital raises cytochrome P-450 concentration. Benzobarbital can be used in the research of post-ischemic liver disease[1][2].
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Benzobarbital | Benzobarbital is an active low-toxicity inductor of the liver monooxygenase system. Benzobarbital raises cytochrome P-450 concentration. Benzobarbital can be used in the research of post-ischemic liver disease. | |||||||||||||||||||||
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References
- [1]. Novozheeva T P, et al. The Effects of Benzonal, Halonal, and Halodif on the Development of Postischemic Liver Disorders in Rats. Pharmaceutical Chemistry Journal, 2003, 37(12).
- [2]. Novozheeva TP, et al. Benzonal--induktor monooksigenaznoĭ sistemy fenobarbitalovogo tipa [Benzonal--a phenobarbital-type of inducer of the mono-oxygenase system]. Biull Eksp Biol Med. 1991 Feb;111(2):163-5. Russian. [Content Brief]
Keywords
