7643-08-5
7643-08-5
Chemical Structure
2-Methylthiophenothiazine
- CAS. Nr.: 7643-08-5
- Formula:C13H11NS2
- Molecular Weight:245.36
IUPAC Name: 2-(Methylthio)-10H-phenothiazine
InChIKey: OBVKBOLDEFIQDP-UHFFFAOYSA-N
SMILES: CSC1=CC(NC2=CC=CC=C2S3)=C3C=C1
Biological Activity: 2-Methylthiophenothiazine (compound 17) is a precursor of tubulin inhibitor with potential anticancer activity and can inhibit tubulin aggregation[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
2-Methylthiophenothiazine | 99.0% | 2-Methylthiophenothiazine (compound 17) is a precursor of tubulin inhibitor with potential anticancer activity and can inhibit tubulin aggregation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63. [Content Brief]
- [2]. Glass-Marmor L, et al. Calmodulin antagonists decrease glucose 1,6-bisphosphate, fructose 1,6-bisphosphate, ATP and viability of melanoma cells. Eur J Pharmacol. 1996 Oct 17;313(3):265-71. [Content Brief]
Keywords
