81264-57-5
Chemical Structure
(-)-MDO-NPA
- CAS No.: 81264-57-5
- Formula:C20H21NO2
- Molecular Weight:307.39
IUPAC Name: (R)-7-propyl-6a,7,8,9-tetrahydro-6H-[1,3]dioxolo[4',5':5,6]benzo[1,2-g]benzo[de]quinoline
InChIKey: YSONYEIWWIFWEV-MRXNPFEDSA-N
SMILES: CCCN1[C@@]2([H])C3=C(CC1)C=CC=C3C4=C(C2)C=CC5=C4OCO5
Biological Activity: (-)-MDO-NPA is an N-propylnorapomorphine analog and a D1R/D2R dual-target ligand. (-)-MDO-NPA has EC50 values of 1949 nM (D1R) and 520 nM (D2R) for β-arrestin. (-)-MDO-NPA has EC50 values of 717.5 nM (D1R) and 7.7 nM (D2R) for cAMP. (-)-MDO-NPA can be used in the research of dopamine-related diseases such as Parkinson’s disease[1].
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(-)-MDO-NPA | (-)-MDO-NPA is an N-propylnorapomorphine analog and a D1R/D2R dual-target ligand. (-)-MDO-NPA has EC50 values of 1949 nM (D1R) and 520 nM (D2R) for β-arrestin. (-)-MDO-NPA has EC50 values of 717.5 nM (D1R) and 7.7 nM (D2R) for cAMP. (-)-MDO-NPA can be used in the research of dopamine-related diseases such as Parkinson’s disease. | |||||||||||||||||||||
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Keywords
