869493-21-0
869493-21-0
Chemical Structure
PRX-03140
Synonym(s): VRX-03011 free base
- CAS No.: 869493-21-0
- Formula:C19H27N3O3S
- Molecular Weight:377.50
IUPAC Name: 4-hydroxy-7-isopropyl-6-oxo-N-(3-(piperidin-1-yl)propyl)-6,7-dihydrothieno[2,3-b]pyridine-5-carboxamide
InChIKey: SCHKZZSVELPJKU-UHFFFAOYSA-N
SMILES: O=C(NCCCN1CCCCC1)C=2C(=O)N(C=3SC=CC3C2O)C(C)C
Biological Activity: PRX-03140 is a selective, blood-brain-barrier permeable 5-HT4 receptor agonist with a Ki value of 110 nM against rat brain 5-HT4 receptor. PRX-03140 can increase cortical ACh and histamine levels. PRX-03140 can be used in the research of Alzheimer's disease[1].
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PRX-03140 | PRX-03140 is a selective, blood-brain-barrier permeable 5-HT4 receptor agonist with a Ki value of 110 nM against rat brain 5-HT4 receptor. PRX-03140 can increase cortical ACh and histamine levels. PRX-03140 can be used in the research of Alzheimer's disease. | |||||||||||||||||||||
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