CC-17369 hydrochloride
CC-17369 (7-Hydroxy pomalidomide) hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CC-17369 (7-Hydroxy pomalidomide) hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- Formula: C13H12ClN3O5
- Molecular Weight:325.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 325.70
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Formula C13H12ClN3O5
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SMILES
O=C1N(C(C2=C1C(O)=CC=C2N)=O)C(C(N3)=O)CCC3=O.Cl
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Synonyms
7-Hydroxy pomalidomide hydrochloride; Pomalidomide metabolite M16 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)