CGS-12066 maleate
CGS-12066 (maleate) is a 5-HT receptor agonist. CGS-12066 has agonist effect for 5-HT1A , 5-HT1B ,5-HT1C and 5-HT1D with pEC50 values of 6.41, 7.56, 4.05 and 7.11, respectively. CGS-12066 can be used for the research of neurological disease.
For research use only. We do not sell to patients.
- CAS No.: 1350965-83-1
- Formula: C21H21F3N4O4
- Molecular Weight:450.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1A Receptor |
5-HT1B Receptor |
5-HT1C Receptor |
5-HT1D Receptor |
CGS-12066 (maleate) has agonist effect for 5-HT1A, 5-HT1B,5-HT1C and 5-HT1D with pEC50 values of 6.41, 7.56, 4.05 and 7.11, respectively[1].
CGS-12066 (maleate) has agonist effect for 5-HT1A, 5-HT1B,5-HT1C and 5-HT1D with pKD values of 7.19, 6.94, 4.89 and 7.49, respectively[1].
CGS-12066 (maleate) stimulates accumulation of inositol phosphates with low potency[1].
CGS-12066 (maleate) acts as partial agonist in inhibiting forskolin-stimulated adenylate cyclase activity in calf substantia nigra[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1350965-83-1
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Molecular Weight 450.41
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Formula C21H21F3N4O4
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SMILES
CN1CCN(CC1)C2=NC3=C(C=CC(C(F)(F)F)=C3)N4C2=CC=C4.O=C(/C=C\C(O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CGS-12066 maleate Related Classifications
HY-123704 Related Classifications
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