RP 73163 Racemate
RP 73163 Racemate is the racemate of RP 73163. RP 73163 is a potent ACAT inhibitor, with cholesterol lowering activity.
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- CAS. Nr.: 136609-53-5
- Formel: C25H28N4OS
- Molecular Weight:432.58
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
108 nM
Compound: 5
|
Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from HEP G2 cells.
Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from HEP G2 cells.
|
10.1016/0960-894X(95)00555-8 |
| THP-1 | IC50 |
164 nM
Compound: 5
|
Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from THP-1 cells.
Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from THP-1 cells.
|
10.1016/0960-894X(95)00555-8 |
Chemical Information
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CAS. Nr. 136609-53-5
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Molecular Weight 432.58
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Formel C25H28N4OS
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SMILES
CC1=CC(C)=NN1CCCCCS(C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)