BBX - BBX high mobility group box domain containing Gene
Also Known as HBP2; ARTC1; MDS001; HSPC339
Species: Homo sapiens
About BBX
This gene has 26 transcripts (splice variants), 199 orthologues and 1 paralogue. Broad expression in testis (RPKM 26.5), thyroid (RPKM 14.4) and 24 other tissues.
Summary
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within bone development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
BBX Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001142568.3 | NP_001136040.1 | HMG box transcription factor BBX isoform 1 |
| NM_001276286.2 | NP_001263215.1 | HMG box transcription factor BBX isoform 3 |
| NM_020235.7 | NP_064620.2 | HMG box transcription factor BBX isoform 2 |
BBX Protein Structure
HMG_box: HMG (high mobility group) box (81 - 148)
DUF2028: Domain of unknown function (DUF2028) (191 - 323)
- 0
- 200
- 400
- 600
- 800
- 941 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
HMG box transcription factor BBX |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Hemolytic Disease Of Fetus And Newborn, Rh-Induced |
|
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Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS01392 | BBX Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | BBX | RGD | RGD:1309769 |
| Felis catus | BBX | VGNC | VGNC:60076 |
| Bos taurus | BBX | VGNC | VGNC:26433 |
| Mus musculus | BBX | MGD | MGI:1917758 |
| Canis familiaris | BBX | VGNC | VGNC:38394 |
| Macaca mulatta | BBX | VGNC | VGNC:82110 |
| Others | BBX | NCBI |
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