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Art. -Nr.: HY-161751

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MJ34

MJ34 is a potent inhibitor of GSK-3β and GSK-3α, with the IC₅₀s of 15.4 nM and 31.5 nM, respectively. MJ34 plays an important role in cancer research

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2099015-13-9
Formel: C₁₉H₁₇N₅
Molecular Weight:315.37

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MJ34 Chemical Structure

CAS. Nr.: 2099015-13-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

MJ34 is a potent inhibitor of GSK-3β and GSK-3α, with the IC₅₀s of 15.4 nM and 31.5 nM, respectively. MJ34 plays an important role in cancer research^[1]

IC₅₀ & Target

GSK-3β

15.4 nM (IC₅₀)

GSK-3α

31.5 nM (IC₅₀)

Alle GSK-3 Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 2099015-13-9
Molecular Weight 315.37
Formel C₁₉H₁₇N₅
SMILES

NC1=NC=CC(C2=CNC3=NC=C(C=C32)C4=C(CC)C=CC=C4)=N1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Mir Owais Ayaz, et al. Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner. Life Sci. 2024 Aug 15:351:122840. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=

Konzentration Konzentration

×

Volumen Volumen

×

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

×

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

=

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

×

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise