Naxaprostene
Naxaprostene is a prostacyclin analogue. Naxaprostene was much more selective for IP receptors and tended towards partial agonism. Naxaprostene inhibits ADP-induced platelet aggregation. It has been shown to prevent rabbit carotid artery thrombosis.
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- CAS. Nr.: 87269-59-8
- Formel: C25H32O4
- Molecular Weight:396.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 87269-59-8
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Molecular Weight 396.52
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Formel C25H32O4
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SMILES
O[C@@H](C1CCCCC1)/C=C/[C@@H]2[C@]3([H])[C@@](C[C@H]2O)([H])C/C(C3)=C\C4=CC(C(O)=O)=CC=C4
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Synonyms
EL 784
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Maurin, N. Influence on platelet activity and red cell fluidity of epoprostenol and two stable prostacyclin analogues in vitro. Arzneimittelforschung 36(8), 1180-1183 (1986). [Content Brief]
[2]. Syed NI, Jones RL. Assessing the agonist profiles of the prostacyclin analogues treprostinil and naxaprostene, particularly their DP₁ activity. Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:19-29. doi: 10.1016/j.plefa.2014.11.011. Epub 2014 Dec 5. PMID: 25542069. [Content Brief]
[3]. Schneider J. Antithrombotic effects of the prostacyclin analogue naxaprostene after oral and intraduodenal application in rabbit carotid artery thrombosis. Agents Actions Suppl. 1992;37:176-82. doi: 10.1007/978-3-0348-7262-1_24. PMID: 1632291. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Naxaprostene Related Classifications
HY-165434 Related Classifications
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