P2RY13 - purinergic receptor P2Y13 Gene

Also Known as GPCR1; GPR86; GPR94; P2Y13; SP174; FKSG77

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 53829

About P2RY13

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:151,326,312-151,329,549 (from NCBI)

This gene has 1 transcript (splice variant), 115 orthologues and 6 paralogues. Broad expression in spleen (RPKM 21.1), appendix (RPKM 14.3) and 18 other tissues.

Summary

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]

P2RY13 Products (3)

mRNA Protein Name
NM_176894.3 NP_795713.2 P2Y purinoceptor 13
XM_006713664.1 XP_006713727.1 P2Y purinoceptor 13 isoform X1
NM_023914.2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

P2RY13 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (62 - 317)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 13

  • G protein-coupled receptor 86

  • G-protein coupled receptor 94

  • purinergic receptor P2Y, G-protein coupled, 13

P2RY13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
P2RY13 Q9BPV8 GJA8 Homo sapiens P48165
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS09922 P2RY13 Human Pre-designed siRNA Set A / Unkown
HY-RS09923 P2ry13 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09924 P2ry13 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta P2RY13 VGNC VGNC:83950
Felis catus P2RY13 VGNC VGNC:102795
Bos taurus P2RY13 VGNC VGNC:32526
Mus musculus P2RY13 MGD MGI:1921441
Rattus norvegicus P2RY13 RGD RGD:1302941
Canis familiaris P2RY13 VGNC VGNC:44215
Others P2RY13 NCBI