2. Others Neuronal Signaling Autophagy Immunology/Inflammation NF-κB GPCR/G Protein Apoptosis PI3K/Akt/mTOR
  3. p62 Pyroptosis Autophagy Keap1-Nrf2 mTOR Reference Standards mAChR Histamine Receptor IKK Apoptosis
  4. Clemastine fumarate (Standard)

Clemastine fumarate (Standard)  (Synonyms: HS-592 fumarate (Standard); Meclastine fumarate (Standard))

Cat. No.: HY-B0298AR Purity: 98%
Handling Instructions Technical Support

Clemastine (HS-592; Meclastine) fumarate (Standard) is the analytical standard of Clemastine fumarate. This product is intended for research and analytical applications. Clemastine fumarate is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine fumarate also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine fumarate exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation .

For research use only. We do not sell to patients.

Clemastine fumarate (Standard)

Clemastine fumarate (Standard) Chemical Structure

CAS No. : 14976-57-9

Size Price Stock Quantity
5 mg Get quote 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
10 mg Get quote 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
25 mg Get quote 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
50 mg Get quote 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
100 mg Get quote 4 - 6 weeks 3-5 weeks 5 - 7 weeks 4-6 weeks
200 mg   Get quote  
500 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Clemastine fumarate (Standard):

Top Publications Citing Use of Products

  • Product Information

  • Purity & Documentation

  • Customer Review

Information

Clemastine (HS-592; Meclastine) fumarate (Standard) is the analytical standard of Clemastine fumarate. This product is intended for research and analytical applications. Clemastine fumarate is an orally active, blood-brain barrier-permeable H1 histamine receptor (H1 histamine receptor) antagonist with potent antiallergic effects. Clemastine fumarate also antagonizes muscarinic acetylcholine receptors (mAChR), particularly the M1 and M4 subtypes. In addition to antihistamine effects, Clemastine fumarate exhibits multiple pharmacological activities, especially in promoting central nervous system remyelination, activating autophagy and pyroptosis, exerting anti-apoptotic and neuroprotective effects, and suppressing inflammation .

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

459.96

Formula

C25H30ClNO5
CAS No.
SMILES

CN1[C@@H](CCO[C@](C2=CC=CC=C2)(C3=CC=C(Cl)C=C3)C)CCC1.O=C(O)/C=C/C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Clemastine fumarate (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clemastine fumarate (Standard)14976-57-9HS-592 fumarate (Standard) Meclastine fumarate (Standard)p62PyroptosisAutophagyKeap1-Nrf2mTORReference StandardsmAChRHistamine ReceptorIKKApoptosisSequestosome-1SQSTM1Mammalian target of RapamycinMuscarinic acetylcholine receptorIκB kinaseI kappa B kinase Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Clemastine fumarate (Standard)
Cat. No.:
HY-B0298AR
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.