COX-2/5-LOX-IN-6
COX-2/5-LOX-IN-6 (Compound 4c) is a potent and selective 5-LOX (IC50 = 0.10 μM) and COX-2 (IC50: 2.88 μM) inhibitor. COX-2/5-LOX-IN-6 displays potent anticancer activity against ovarian cancer. COX-2/5-LOX-IN-6 would not cause cytotoxic effects in noncancerous cells. COX-2/5-LOX-IN-6 is a potential anti-inflammatory agent.
For research use only. We do not sell to patients.
- Formula: C25H23FeN3O4S
- Molecular Weight:517.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
5-LOX 0.10 μM (IC50) |
COX-2 2.88 μM (IC50) |
Chemical Information
-
Molecular Weight 517.38
-
Formula C25H23FeN3O4S
-
SMILES
O=S(N)(C1=CC=C(N2C(C3=CC(O)=C(O)C=C3)CC(c4cccc4)=N2)C=C1)=O.[][Fe][].c5cccc5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)