CRBN ligand-911
CRBN ligand-911 is an E3 ligase ligand that targets CRBN. CRBN ligand-911 forms a stable ternary complex with CRBN to enable proximity-induced co-binding and ubiquitination of LIMK2. CRBN ligand-911 binds directly to CRBN. CRBN ligand-911 is used for the synthesis of the LIMK2-targeting PROTAC degrader THNAN69 (HY-178122).
For research use only. We do not sell to patients.
- Formula: C14H14N2O3
- Molecular Weight:258.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
Chemical Information
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Molecular Weight 258.27
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Formula C14H14N2O3
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SMILES
CC1=C(N2CCC(NC2=O)=O)C=CC=C1OCC#C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CRBN ligand-911 Related Classifications
HY-189495 Related Classifications
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