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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
83 Results for "
MMP-3
" in MedChemExpress (MCE) Product Catalog:
Products (83)
83 Results for "MMP-3" in MCE Product Catalog:
Cat. No.: HY-N1454R
CAS No.: 29741-09-1
Synonyms: Apigenin 7-O-glucuronide (Standard)
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants
Target:
Cat. No.: HY-P2185
CAS No.: 158584-09-9
Cat. No.: HY-P3202
CAS No.: 79955-99-0
Synonyms: MMP-3; Stromelysin-1
Target:
Research Areas:
Matrix metalloproteinase 3 (MMP-3) is a member of the class of zinc-dependent proteases that can degrade the extracellular matrix (ECM). Matrix metalloproteinase 3 palys an important role in the neuronal apoptotic process as well as in neuroinflammation. Matrix metalloproteinase 3 can be used in the study of neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
Cat. No.: HY-N16408
CAS No.: 1019854-22-8
Category:
Cat. No.: HY-RS08550
Target:
Research Areas:
Mmp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-152030
CAS No.: 2734877-51-9
Target:
Research Areas:
Tubulin/MMP-IN-2 is dual inhibitor of tubulin and matrix metalloproteinases. Tubulin/MMP-IN-2 can strongly inhibit tubulin polymerization and induces cell apoptosis. Tubulin/MMP-IN-2 has inhibitory activities against MMP-2, MMP-3 and MMP-9 with IC50 values of 24.95 μM, 31.60 μM and 22.37 μM, respectively. Tubulin/MMP-IN-2 can be used for the research of cancer .
Cat. No.: HY-P3098
CAS No.: 256394-94-2
Cat. No.: HY-167825
CAS No.: 24506-68-1
Cat. No.: HY-18694
CAS No.: 169799-04-6
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Research Areas:
CGS 27023A is a non-peptidic and orally active MMP inhibitor with the Ki values of 43, 33, 20 and 8 nM for MMP-3, MMP-1, MMP-2 amd MMP-9, respectively. CGS 27023A prevents cartilage degradation in stromelysin-induced rabbit cartilage degradation model. CGS 27023A can be used for study of arthritis .
Cat. No.: HY-117464
CAS No.: 1664361-37-8
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Research Areas:
CM-352 (compound 5) is an inhibitor of matrix metalloproteinases (MMPs) (MMP-3: IC50=15 nM; MMP-10: IC50=12 nM). CM-352 has significant antifibrinolytic activity (EC50=0.7 nM) and can significantly prolong blood coagulation time. CM-352 can be used in anti-bleeding research .
Cat. No.: HY-15768R
CAS No.: 142880-36-2
Synonyms: GM6001 (Standard); Galardin (Standard)
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Research Areas:
Ilomastat (Standard) is the analytical standard of Ilomastat. This product is intended for research and analytical applications. Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1).
Cat. No.: HY-137370
CAS No.: 141018-30-6
Synonyms: HENECA; 2-Hexynyl-NECA
Target:
Research Areas:
2-Hexynyl-5′-N-ethylcarboxamidoadenosine (HENECA) is a selective A2A adenosine receptor agonist. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine increases intracellular cAMP level, and inhibits TNFα-evoked MMP-3 release. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine induces Aβ42 production in SH-SY5Y cells [3].
Cat. No.: HY-N1463R
CAS No.: 29741-10-4
Synonyms: Luteolin 7-glucuronide (Standard)
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants
Target:
Cat. No.: HY-12270R
CAS No.: 530141-72-1
T-5224 (Standard) is the analytical standard of T-5224. This product is intended for research and analytical applications. T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription .
Cat. No.: HY-110397G
CAS No.: 1365803-52-6
Cat. No.: HY-P3699A
Target:
Research Areas:
TNO003 TFA is a selective fluorogenic substrate for stromelysin-1 (MMP-3). TNO003 TFA has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 TFA can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm) .
Cat. No.: HY-107617
CAS No.: 1032822-42-6
Target:
Research Areas:
PTIQ can suppress MMP-3 production, can enter the brain and provide neuroprotection. PTIQ has anti-inflammatory effects on microglial cells .
Cat. No.: HY-N2259R
CAS No.: 19431-84-6
Synonyms: (+)-Curcumenol (Standard)
Synonyms: PG 530742; PGE 530742; PGE 7113313
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Research Areas:
PG 116800 (PGE 530742; PGE 7113313) is an orally active, selective and high-affinity inhibitor of MMP. PG 116800 acts as an inhibitor of ventricular remodeling, reduces left ventricular volumes and infarct zone collagen content, and improves ejection fraction. PG 116800 is generally well tolerated, but is associated with higher rates of arthralgia, joint stiffness, and dyspepsia. PG 116800 can be used for the research of myocardial infarction .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
