2734877-51-9
Chemical Structure
Tubulin/MMP-IN-2
- CAS 番号: 2734877-51-9
- Formula:C40H48NO11P
- Molecular Weight:749.78
IUPAC Name: (Z)-2-(2-methoxy-5-(3,4,5-trimethoxystyryl)phenoxy)ethyl 2-(4-(((diethoxyphosphoryl)(4-methoxyphenyl)methyl)amino)phenyl)acetate
InChIKey: DMYVJNQAJVBXBM-KHPPLWFESA-N
SMILES: CCOP(OCC)(C(C1=CC=C(C=C1)OC)NC2=CC=C(C=C2)CC(OCCOC3=CC(/C=C\C4=CC(OC)=C(C(OC)=C4)OC)=CC=C3OC)=O)=O
Biological Activity: Tubulin/MMP-IN-2 is dual inhibitor of tubulin and matrix metalloproteinases. Tubulin/MMP-IN-2 can strongly inhibit tubulin polymerization and induces cell apoptosis. Tubulin/MMP-IN-2 has inhibitory activities against MMP-2, MMP-3 and MMP-9 with IC50 values of 24.95 μM, 31.60 μM and 22.37 μM, respectively. Tubulin/MMP-IN-2 can be used for the research of cancer[1].
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Tubulin/MMP-IN-2 | Tubulin/MMP-IN-2 is dual inhibitor of tubulin and matrix metalloproteinases. Tubulin/MMP-IN-2 can strongly inhibit tubulin polymerization and induces cell apoptosis. Tubulin/MMP-IN-2 has inhibitory activities against MMP-2, MMP-3 and MMP-9 with IC50 values of 24.95 μM, 31.60 μM and 22.37 μM, respectively. Tubulin/MMP-IN-2 can be used for the research of cancer. | |||||||||||||||||||||
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Keywords
