Droxicam

Droxicam (0.25 and 0.5 mg/kg; po) shows high antiinflammatory activity in carrageenin-induced edema in rat^[1].
Droxicam (ED50, p.o.; 5, 6, 7, 8 h; 7.5, 12.9, 4.8, 8.4 mg/kg) shows high antiinflammatory activity against nystatin-induced edema in rat^[1].
Droxicam (ED50, p.o., 1, 2, 3, 4 h: 0.51, 0.94, 1.56, 4.88 mg/kg) shows protective effects in U.V. light-induced erythema in guinea pigs^[1].
Droxicam (0.1 mg/kg, 0.33 mg/kg, 1 mg/kg; po; once daliy) shows good antiarthritic activity in rats injected with Mycobacterium butyricum against primary and secondary lesions^[1].
Droxicam demonstrates strong analgesic activity in protecting against writhings : induced by phenylbenzoquinone in mice, induced by acetylcholine bromide in mice, with ED50s of 5.3 mg/kg and 1.1 mg/kg, respectively^[1].
Droxicam (ED50=0.081 mg/kg; po) protects rat against diarrhea induced by castor oil^[1].
Droxicam significantly inhibits peritoneal capillary permeability in mice^[1].
Droxicam does not alter rat behavior (80 mg/kg, i.p.) nor that of mice (160 mg/kg, p.o.) in the Irwin's test^[1].
Droxicam does not exhibit uricosuric activity in rats, neither shows cardiovascular or respiratory effects in anesthetized cats, nor modify their response to administration of acetylcholine, norepinephrine and histamine^[1].