Azide Reactive Dyes

AF405 DBCO is a blue fluorescent dye derivative containing a dibenzocyclooctyne (DBCO) group. AF405 DBCO reacts rapidly with azide-labeled biomolecules at room temperature without the need for a metal catalyst, enabling copper-free click chemistry (SPAAC) for applications in live-cell imaging, flow cytometry, super-resolution microscopy, and other research fields.

AF594 Picolyl Azide is a composite fluorescent probe formed by covalent linkage of the Alexa Fluor 594 fluorophore and the Picolyl Azide functional group via chemical bonds. AF594 Picolyl Azide contains a copper chelation domain, and through the copper-catalyzed azide-alkyne cycloaddition click chemistry reaction, it can covalently label alkyne-bearing target molecules and generate fluorescent detection signals. AF594 Picolyl Azide can be used for the detection of alkyne-modified sialylated glycoconjugates, and can also label nascent bacterial polypeptides to determine bacterial protein synthesis rates.

6-JOE azide, CHC-protected, is a derivative of JOE (dimethoxy-dichloro-carboxyfluorescein) featuring an azide group for use in click chemistry reactions (CuAAC); it incorporates a CHC (cyclohexylcarbodiimide) protecting group to ensure stability during oligonucleotide synthesis. 6-JOE azide, CHC-protected, is primarily used for click chemistry-based bioconjugation (Ex/Em = 520/548 nm).

5-JOE azide, CHC-protected, is a derivative of JOE. It features an azide group for use in click chemistry reactions (CuAAC) and a CHC (cyclohexylcarbodiimide) protecting group for stable oligonucleotide synthesis. 5-JOE azide, CHC-protected, is suitable for click chemistry-based bioconjugation (Ex/Em = 520/548 nm) .

6-JOE alkyne is a derivative of JOE featuring a terminal alkyne group, designed for use in click chemistry reactions (CuAAC) . 6-JOE alkyne is suitable for click chemistry-based bioconjugation (Ex/Em = 520/548 nm) .

Coumarin 343 C3 azide is a coumarin derivative containing an azide group, used in click chemistry reactions (CuAAC). It is primarily applied in click chemistry-based bioconjugation (Ex/Em = 445/473 nm).

5-FAM C3 alkyne is a derivative of 6-carboxyfluorescein (6-FAM) featuring a terminal alkyne group, designed for use in click chemistry reactions (CuAAC). It is primarily applied in click chemistry-based bioconjugation (Ex/Em = 495/519 nm).

5-JOE alkyne (CHC-protected) is a JOE derivative featuring a terminal alkyne group for use in click chemistry reactions (CuAAC) ; the CHC (cyclohexyl carbodiimide) protecting group ensures stability during oligonucleotide synthesis. 5-JOE alkyne (CHC-protected) is suitable for click chemistry-based bioconjugation (Ex/Em = 520/548 nm) .

6-TAMRA BCN is a derivative of TAMRA (tetramethylrhodamine) featuring a BCN (bicyclo[6.1.0]nonyne) group, designed for copper-free click chemistry reactions. 6-TAMRA BCN is primarily used for copper-free click chemistry-based bioconjugation (Ex/Em = 553/576 nm).

5-JOE alkyne is a derivative of JOE featuring a terminal alkyne group, designed for use in click chemistry reactions (CuAAC) . 5-JOE alkyne is suitable for click chemistry-based bioconjugation (Ex/Em = 520/548 nm) .

6-FAM BCN is a derivative of 6-carboxyfluorescein (6-FAM) featuring a BCN (bicyclo[6.1.0]nonyne) group, designed for copper-free click chemistry reactions. 6-FAM BCN is primarily used for copper-free click chemistry-based bioconjugation (Ex/Em = 495/519 nm).

6-JOE alkyne (CHC-protected) is a derivative of JOE (dimethoxy-dichloro-carboxyfluorescein) featuring a terminal alkyne group for use in click chemistry reactions (CuAAC); the CHC (cyclohexylcarbodiimide) protecting group ensures stability during oligonucleotide synthesis. 6-JOE alkyne (CHC-protected) is primarily used for click chemistry-based bioconjugation (Ex/Em = 520/548 nm).

5-JOE BCN is a derivative of JOE featuring a BCN (bicyclo[6.1.0]nonyne) group, designed for copper-free click chemistry reactions. 5-JOE BCN can be used for copper-free click chemistry-based bioconjugation (Ex/Em = 520/548 nm) .

6-FAM-PEG2-azide is a derivative of 6-carboxyfluorescein (6-FAM) featuring an azide group for use in click chemistry reactions (CuAAC). It incorporates a PEG2 linker to enhance solubility and reduce steric hindrance. 6-FAM-PEG2-azide is primarily used for click chemistry-based bioconjugation (Ex/Em = 495/519 nm).

Azido-Bodipy-FL-510 is a derivative of BODIPY-FL-510 containing an azide group, designed for use in click chemistry reactions (CuAAC). It is primarily used for click chemistry-based bioconjugation (Ex/Em = 510/520 nm).

AF647-PEG12-TCO is a derivative of Alexa Fluor 647 featuring a TCO (trans-cyclooctene) group for use in inverse-electron-demand Diels-Alder (IEDDA) click chemistry reactions. It incorporates a PEG12 linker to enhance hydrophilicity and provide increased spacer length. AF647-PEG12-TCO is primarily used for IEDDA click chemistry-based bioconjugation (Ex/Em = 650/668 nm).

AF488-PEG12-DBCO is a derivative of Alexa Fluor 488 featuring a DBCO (dibenzocyclooctyne) group for copper-free click chemistry (SPAAC). It incorporates a PEG12 linker to enhance hydrophilicity and provide increased spacer length. AF488-PEG12-DBCO is primarily used for copper-free click chemistry (SPAAC) bioconjugation (Ex/Em = 495/519 nm).

AF594-PEG12-DBCO is a derivative of Alexa Fluor 594 featuring a DBCO (dibenzocyclooctyne) group for copper-free click chemistry (SPAAC). It incorporates a PEG12 linker to enhance hydrophilicity and provide increased spacer length. AF594-PEG12-DBCO is primarily used for copper-free click chemistry (SPAAC) bioconjugation (Ex/Em = 590/617 nm).

AF555-PEG12-DBCO is a derivative of Alexa Fluor 555 featuring a DBCO (dibenzocyclooctyne) group for copper-free click chemistry (SPAAC). It incorporates a PEG12 linker to enhance hydrophilicity and provide spacer distance. AF555-PEG12-DBCO is primarily used for copper-free click chemistry (SPAAC) bioconjugation (Ex/Em = 555/565 nm).

AF405-PEG12-DBCO is a derivative of Alexa Fluor 405 featuring a DBCO (dibenzocyclooctyne) group for copper-free click chemistry (SPAAC). It incorporates a PEG12 linker to enhance hydrophilicity and provide increased spacer length. AF405-PEG12-DBCO is primarily used for copper-free click chemistry (SPAAC) bioconjugation (Ex/Em = 402/421 nm).