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  3. Etidronic acid disodium

Etidronic acid disodium (Synonyms: Etidronate disodium; HEDPA disodium; HEDP disodium)

Cat. No.: HY-B0302A
Handling Instructions

Etidronic acid (Etidronate) disodium is an orally and intravenously active bisphosphonate. Etidronic acid disodium inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid disodium has anticancer activity. Etidronic acid disodium is a chelating agent and can be used to remove heavy metal in water.

For research use only. We do not sell to patients.

Etidronic acid disodium Chemical Structure

Etidronic acid disodium Chemical Structure

CAS No. : 7414-83-7

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500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Etidronic acid (Etidronate) disodium is an orally and intravenously active bisphosphonate. Etidronic acid disodium inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid disodium has anticancer activity. Etidronic acid disodium is a chelating agent and can be used to remove heavy metal in water[1][2][3][4].

In Vitro

Etidronic acid (Etidronate) (10 mM, 24 h) disodium shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells[3].
Etidronic acid (100 nM, 24 h) disodium induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

249.99

Formula

C2H6Na2O7P2

CAS No.
SMILES

OC(P(O)(O[Na])=O)(P(O)(O[Na])=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
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Etidronic acid disodium
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HY-B0302A
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