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Referencia número: HY-105483

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MDL 43291

MDL 43291 is a competitive leukotriene (LT) receptor antagonist. MDL 43291 antagonize LTD4 and LTE4 with pA2 of 6.7. MDL 43291 does not antagonize histamine, carbachol or substance P. MDL 43291 can be used for the researches of inflammation and immunology, such as asthma.

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No. CAS: 129357-91-1
Fòrmula: C₂₅H₄₂O₄S
Peso molecular:438.66

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

MDL 43291 Chemical Structure

No. CAS: 129357-91-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
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Actividad biológica

Descripciòn

IC₅₀ & Target^[1]

LTD₄

6.7 (pA2)

LTE₄

6.7 (pA2)

Ver todos los productos específicos de isoformas Leukotriene Receptor :

In Vivo

MDL 43291 (10-30 mg/kg, i.v.) effectively inhibits increases in insufflation pressure induced by LTD4 in guinea pig^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 129357-91-1
Peso molecular 438.66
Fòrmula C₂₅H₄₂O₄S
SMILES

OC(CS[C@H]1[C@@](O2)([H])[C@](CCC2=O)([H])CC/C1=C/CCCCCCCCCCCCC)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Gieske TH, et al. Conformationally restricted leukotriene receptor antagonists: [(octahydro-2-oxo-7-tetradecylidene-2H-1-benzopyran-8-yl)thio]ace tic acids. Pharmacology. 1990;40(5):271-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureza y Documentación
Referencias

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MDL 43291

Ver todos los productos específicos de isoformas Leukotriene Receptor