SC-50605
SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases..
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 138828-39-4
- Fòrmula: C30H35NO6S
- Peso molecular:537.67
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Leukotriene Receptor
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Actividad biológica
Descripciòn
IC50 & Target
LTB4[1]
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
660 nM
Compound: 35
|
Inhibitory activity against LTB4 production in HL60s.
Inhibitory activity against LTB4 production in HL60s.
|
[PMID: 7699700] |
| HL-60 | IC50 |
928 nM
Compound: 35
|
Inhibitory activity against PGE-2 production in HL60s.
Inhibitory activity against PGE-2 production in HL60s.
|
[PMID: 7699700] |
Chemical Information
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No. CAS 138828-39-4
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Peso molecular 537.67
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Fòrmula C30H35NO6S
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SMILES
O=C(O)C1CCC2=CC=C(C(CCC)=C2O1)OCCCOC3=CC=C(C(OC)=C3CC4CC4)C5=CSC=N5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)