SKF 100398
Based on 1 Customer Validation
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP.
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- Pureza: 99.48%
- No. CAS: 77453-01-1
- Fòrmula: C53H77N13O11S2
- Peso molecular:1136.39
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas Vasopressin Receptor
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Actividad biológica
SKF 100398 (8 μg/kg; i.v.) abolishes the antidiuretic effect of AVP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (250-300 g)[1]
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Dosage:8 μg/kg
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Administration:Intravenous injection
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Result:Completely blocked the antidiuretic effect of exogenous AVP (4 ng/kg body wt i.v.).
{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-Phe-Val-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: 1-Cys6)
{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-YFVNCPRG-NH2 (Disulfide bridge: 1-Cys6)
Chemical Information
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No. CAS 77453-01-1
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Appearance Solid
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Peso molecular 1136.39
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Fòrmula C53H77N13O11S2
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Color White to off-white
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Synonyms
d(CH2)5Tyr(Et)VAVP
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureza y Documentación
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Ficha de datos (260 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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