ZNF717 - zinc finger protein 717 Gene

Also Known as OB1; X17; ZNF838

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100131827

About ZNF717

Cytogenetic location: 3p12.3 Genomic coordinates (GRCh38): 3:75,694,701-75,785,549 (from NCBI)

This gene has 7 transcripts (splice variants), 20 orthologues and 174 paralogues. Ubiquitous expression in testis (RPKM 1.7), thyroid (RPKM 1.6) and 25 other tissues.

Summary

This gene encodes a Kruppel-associated box (KRAB) zinc-finger protein, which belongs to a large group of transcriptional regulators in mammals. These proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation and Apoptosis, and in regulating viral replication and transcription. A pseudogene of this gene was identified on chromosome 1. [provided by RefSeq, May 2016]

ZNF717 Products (7)

mRNA Protein Name
NM_001128223.3 NP_001121695.1 zinc finger protein 717 isoform a
NM_001290208.3 NP_001277137.1 zinc finger protein 717 isoform a
NM_001290209.3 NP_001277138.1 zinc finger protein 717 isoform b
NM_001290210.2 NP_001277139.1 zinc finger protein 717 isoform c
NM_001324026.2 NP_001310955.1 zinc finger protein 717 isoform c
NM_001324027.1 NP_001310956.1 zinc finger protein 717 isoform d
NM_001324028.1 NP_001310957.1 zinc finger protein 717 isoform e

ZNF717 Protein Structure

KRAB

KRAB: KRAB box (15 - 55)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (263 - 283)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (320 - 342)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (347 - 370)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (375 - 398)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (403 - 427)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (431 - 453)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (458 - 482)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (487 - 510)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (515 - 539)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (543 - 566)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (571 - 594)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (601 - 622)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (626 - 650)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (738 - 760)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (765 - 789)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (794 - 817)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (824 - 845)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (850 - 872)

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  • 907 a.a.
Protein Preferred Names Protein Names

zinc finger protein 717

  • krueppel-like factor X17

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16170 ZNF717 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZNF717 RGD RGD:1306633
Mus musculus ZNF717 MGD MGI:99183