PKM - pyruvate kinase, muscle Gene

Also Known as PK-S

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100158154

About PKM

Primary_assembly 7: 61,013,723-61,032,777 forward strand.Sscrofa11.1:CM000818.5

This gene has 3 transcripts (splice variants), 309 orthologues and 1 paralogue. Broad expression in longissimus dorsi muscle (RPKM 536.6), psoas major muscle (RPKM 326.) and 7 other tissues.

PKM Products (22)

mRNA Protein Name
XM_005666188.3 XP_005666245.1 pyruvate kinase PKM isoform X7
XM_021099122.1 XP_020954781.1 pyruvate kinase PKM isoform X7
XM_013978108.2 XP_013833562.1 pyruvate kinase PKM isoform X7
XM_021099108.1 XP_020954767.1 poly [ADP-ribose] polymerase 6 isoform X3
XM_021099125.1 XP_020954784.1 pyruvate kinase PKM isoform X8
XM_021099115.1 XP_020954774.1 poly [ADP-ribose] polymerase 6 isoform X6
XM_021099121.1 XP_020954780.1 pyruvate kinase PKM isoform X7
XM_021099117.1 XP_020954776.1 poly [ADP-ribose] polymerase 6 isoform X6
XM_021099111.1 XP_020954770.1 poly [ADP-ribose] polymerase 6 isoform X5
XM_021099124.1 XP_020954783.1 pyruvate kinase PKM isoform X8
XM_021099118.1 XP_020954777.1 pyruvate kinase PKM isoform X7
XM_021099110.1 XP_020954769.1 poly [ADP-ribose] polymerase 6 isoform X4
XM_021099106.1 XP_020954765.1 poly [ADP-ribose] polymerase 6 isoform X1
XM_021099116.1 XP_020954775.1 poly [ADP-ribose] polymerase 6 isoform X6
XM_021099107.1 XP_020954766.1 poly [ADP-ribose] polymerase 6 isoform X2
XM_001929069.5 XP_001929104.1 pyruvate kinase PKM isoform X8
XM_005666187.3 XP_005666244.1 pyruvate kinase PKM isoform X7
XM_021099119.1 XP_020954778.1 pyruvate kinase PKM isoform X7
XM_021099114.1 XP_020954773.1 poly [ADP-ribose] polymerase 6 isoform X6
XM_021099123.1 XP_020954782.1 pyruvate kinase PKM isoform X7
XM_021099113.1 XP_020954772.1 poly [ADP-ribose] polymerase 6 isoform X5
XM_021099109.1 XP_020954768.1 poly [ADP-ribose] polymerase 6 isoform X4

PKM Protein Structure

ADP_ribosyl

ADP_ribosyl: cd01341 (221 - 357)

ADP_ribosyl

ADP_ribosyl: cd01341 (470 - 594)

Pyruvate_Kinase

Pyruvate_Kinase: cd00288 (648 - 1136)

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  • 1000
  • 1138 a.a.
Protein Preferred Names Protein Names

poly [ADP-ribose] polymerase 6

pyruvate kinase PKM

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0404A Benserazide hydrochloride Inhibitor 99.68% Yes
HY-B0404AR Benserazide hydrochloride (Standard) Inhibitor 99.89% Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-P1284 ZIP Inhibitor 98.56% Phase 4
HY-155785 MTP / Phase 4
HY-P1284A ZIP TFA Inhibitor / Phase 4

Pre-clinical Phase

Bioactive Molecules (58)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0822 Shikonin Inhibitor 99.80% Unkown
HY-18657 TEPP-46 Activator 99.93% Unkown
HY-103617 PKM2-IN-1 Inhibitor 99.79% Unkown
HY-19330 DASA-58 Activator 99.57% Unkown
HY-126585 SAICAR 99.57% Unkown
HY-162080 METTL1-WDR4-IN-1 Inhibitor 99.61% Unkown
HY-N7108 7-Hydroxyflavone 99.89% Unkown
HY-157913 PKM2-IN-6 99.95% Unkown
HY-147368 PKM2 activator 2 Activator 99.38% Unkown
HY-167832 PT109 99.20% Unkown
HY-121275 Benserazide Inhibitor 98.43% Yes
HY-139667 PKM2-IN-3 Inhibitor 99.44% Unkown
HY-N2552 Vitamin K5 hydrochloride 99.25% Unkown
HY-D1456 TEPC466 99.43% Unkown
HY-N3011 Iridin 99.72% Unkown
HY-N7064 Iminostilbene Inhibitor 99.34% Unkown
HY-148324 PKM2 activator 5 Activator 96.03% Unkown
HY-148615 NPD10084 Inhibitor 99.69% Unkown
HY-155850 CIAC001 Inhibitor 99.70% Unkown
HY-W587878 Thujopsene 86.31% Unkown
HY-P1399A Pep2m, myristoylated TFA Inhibitor 99.77% Unkown
HY-126585S SAICAR-d3 96.57% Unkown
HY-132215 PF-06284674 Activator 99.69% Unkown
HY-156375 PKM2 activator 6 / Unkown
HY-162080A METTL1-WDR4-IN-1 TFA Inhibitor 99.61% Unkown
HY-179371 LIQ1 Inhibitor 97.40% Unkown
HY-D1876 ZY-2 95.77% Unkown
HY-RS10602 PKM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119874 Alkannin Inhibitor / Unkown
HY-147397 PKM2 activator 3 Activator / Unkown
HY-149275 PKM2/PDK1-IN-1 / Unkown
HY-155216 PKM2 activator 10 Activator / Unkown
HY-155668 HMG-CoA Reductase-IN-1 Inhibitor / Unkown
HY-155849 PKM2-IN-4 Inhibitor / Unkown
HY-161519 PKM2 activator 7 Activator / Unkown
HY-168882 PKM2 modulator 1 / Unkown
HY-168883 PKM2 modulator 2 / Unkown
HY-169567 PKM2-IN-9 Inhibitor / Unkown
HY-170577 PKM2-IN-8 / Unkown
HY-172881 PKM2-IN-10 Inhibitor / Unkown
HY-178441 PKM2-IN-11 / Unkown
HY-178748 PKM2-IN-12 / Unkown
HY-180523 PKM2-IN-13 / Unkown
HY-180795 PKM2 activator 11 / Unkown
HY-182037 Multi-target kinase-IN-9 Inhibitor / Unkown
HY-183765 PARP1/PKM2-IN-1 Inhibitor / Unkown
HY-B0404AS Benserazide-d3 hydrochloride Inhibitor / Unkown
HY-B1814 Vitamin K5 / Unkown
HY-D1877 ZY-1 98.91% Unkown
HY-P1399 Pep2m, myristoylated Inhibitor / Unkown
HY-RS10603 Pkm Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10604 Pkm Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W753956 Iminostilbene-d10 / Unkown
HY-148313 PKM2 activator 4 Activator / Unkown
HY-162071 PKM2-IN-5 Inhibitor / Unkown
HY-168995 BAR-072 Inhibitor / Unkown
HY-169883 PKM2-IN-7 Inhibitor / Unkown
HY-180796 PKM2 agonist-1 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PKM NCBI NCBI:5315