PKM2-IN-10
PKM2-IN-10 (Compound 16) is a PKM2 inhibitor. PKM2-IN-10 inhibits the proliferation of A549 and HCC1833 cell lines with IC50 of 3.36 μM and 9.20 μM, respectively. PKM2-IN-10 exhibits antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. PKM2-IN-10 can be used in lung cancer research.
For research use only. We do not sell to patients.
- Formula: C21H15F4N5
- Molecular Weight:413.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PKM2 |
Chemical Information
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Molecular Weight 413.37
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Formula C21H15F4N5
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SMILES
N=C(N(C)C1=CC(F)=CC(C(F)(F)F)=C1)NC2=CC3=C(N=CC=C3)C4=C2C=CC=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)