PKM2 agonist-1
PKM2 agonist-1 (Compound D16) is a highly effective, allosteric PKM2 agonist with an AC50 value of 77 nM. PKM2 agonist-1 inhibits Ang II-induced smooth muscle cell phenotypic switching. PKM2 agonist-1 effectively prevents aortic dissection and results in reduced mortality.
For research use only. We do not sell to patients.
- CAS No.: 3075162-42-1
- Formula: C24H23N5O4S2
- Molecular Weight:509.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PKM2 |
Chemical Information
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CAS No. 3075162-42-1
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Molecular Weight 509.60
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Formula C24H23N5O4S2
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SMILES
O=S(NC1=CC=C(C=C1)C2=NC=CN2C3CN(C3)S(=O)(C4CC4)=O)(C5=CC=CC6=CC=CN=C65)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)