PKM2 agonist-1
PKM2 agonist-1 (Compound D16) is a highly effective, allosteric PKM2 agonist with an AC50 value of 77 nM. PKM2 agonist-1 inhibits Ang II-induced smooth muscle cell phenotypic switching. PKM2 agonist-1 effectively prevents aortic dissection and results in reduced mortality.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3075162-42-1
- Fòrmula: C24H23N5O4S2
- Peso molecular:509.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
[1]|
PKM2 |
Chemical Information
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No. CAS 3075162-42-1
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Peso molecular 509.60
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Fòrmula C24H23N5O4S2
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SMILES
O=S(NC1=CC=C(C=C1)C2=NC=CN2C3CN(C3)S(=O)(C4CC4)=O)(C5=CC=CC6=CC=CN=C65)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)