2. Metabolic Enzyme/Protease Stem Cell/Wnt JAK/STAT Signaling Apoptosis
  3. Pyruvate Kinase STAT Apoptosis
  4. PKM2 activator 11

PKM2 activator 11 (Compound 23) is a PKM2 activator with an AC50 value of 92.12 nM. PKM2 activator 11 promotes PKM2 tetramerization and inhibits its nuclear translocation. PKM2 activator 11 suppresses glycolysis and the PKM2/STAT3 signaling pathway. PKM2 activator 11 induces Apoptosis. PKM2 activator 11 exhibits anti-CRC activity in vitro with potency and selectivity.

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PKM2 activator 11

PKM2 activator 11 Chemical Structure

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PKM2 activator 11 Related Antibodies

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Description

PKM2 activator 11 (Compound 23) is a PKM2 activator with an AC50 value of 92.12 nM. PKM2 activator 11 promotes PKM2 tetramerization and inhibits its nuclear translocation. PKM2 activator 11 suppresses glycolysis and the PKM2/STAT3 signaling pathway. PKM2 activator 11 induces Apoptosis. PKM2 activator 11 exhibits anti-CRC activity in vitro with potency and selectivity[1].

IC50 & Target[1]

STAT3

 

PKM2

 

Molecular Weight

457.54

Formula

C27H23NO4S
SMILES

O=C(C1=O)C2=C(OC(CN3CCC(SC=C4)=C4C3)=C2C)C5=C1C6=C(C=C5)C(C)(C)C(C=C6)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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PKM2 activator 11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PKM2 activator 11Pyruvate KinaseSTATApoptosisanti-CRCInhibitorinhibitorinhibit

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