PRDM16 - Prdm16 PR/SET domain 16 Gene
Species: Rattus norvegicus
Summary
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; Histone Methyltransferase activity (H3-K9 specific); and transcription coactivator activity. Predicted to be involved in several processes, including brown fat cell differentiation; positive regulation of cold-induced thermogenesis; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of brown fat cell differentiation; and regulation of transcription, DNA-templated. Predicted to be located in aggresome; cytosol; and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Orthologous to human PRDM16 (PR/SET domain 16). [provided by Alliance of Genome Resources, Apr 2022]
PRDM16 Products (8)
| mRNA | Protein | Name |
|---|---|---|
| XM_039111366.1 | XP_038967294.1 | histone-lysine N-methyltransferase PRDM16 isoform X5 |
| XM_039111367.1 | XP_038967295.1 | histone-lysine N-methyltransferase PRDM16 isoform X6 |
| XM_039111365.1 | XP_038967293.1 | histone-lysine N-methyltransferase PRDM16 isoform X4 |
| XM_039111363.1 | XP_038967291.1 | histone-lysine N-methyltransferase PRDM16 isoform X2 |
| XM_039111364.1 | XP_038967292.1 | histone-lysine N-methyltransferase PRDM16 isoform X3 |
| XM_039111368.1 | XP_038967296.1 | histone-lysine N-methyltransferase PRDM16 isoform X7 |
| XM_039111362.1 | XP_038967290.1 | histone-lysine N-methyltransferase PRDM16 isoform X1 |
| XM_039111370.1 | XP_038967298.1 | histone-lysine N-methyltransferase PRDM16 isoform X8 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
PR/SET domain 16 histone-lysine N-methyltransferase PRDM16 |
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