Phkb - phosphorylase kinase beta Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 102093
Summary
Predicted to enable Calmodulin binding activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in plasma membrane. Predicted to be part of Phosphorylase kinase complex. Is expressed in colon; hindgut; and primitive hindgut. Human ortholog(s) of this gene implicated in glycogen storage disease IXb. Orthologous to human PHKB (Phosphorylase kinase regulatory subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
Phkb Products (8)
| mRNA | Protein | Name |
|---|---|---|
| NM_001364411.2 | NP_001351340.1 | phosphorylase b kinase regulatory subunit beta isoform 2 |
| NM_001364412.2 | NP_001351341.1 | phosphorylase b kinase regulatory subunit beta isoform 3 |
| NM_001403917.1 | NP_001390846.1 | phosphorylase b kinase regulatory subunit beta isoform 1 |
| NM_001403918.1 | NP_001390847.1 | phosphorylase b kinase regulatory subunit beta isoform 1 |
| NM_001403919.1 | NP_001390848.1 | phosphorylase b kinase regulatory subunit beta isoform 2 |
| NM_001403920.1 | NP_001390849.1 | phosphorylase b kinase regulatory subunit beta isoform 2 |
| NM_001403921.1 | NP_001390850.1 | phosphorylase b kinase regulatory subunit beta isoform 3 |
| NM_199446.3 | NP_955517.1 | phosphorylase b kinase regulatory subunit beta isoform 1 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in glucose homeostasis |
IMP
IMP: Inferred from mutant phenotype
|
36077341 | MGI |
| involved in positive regulation of glycogen catabolic process |
IMP
IMP: Inferred from mutant phenotype
|
36077341 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
phosphorylase b kinase regulatory subunit beta |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS10439 | PHKB Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS22278 | Phkb Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28801 | Phkb Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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