Maml1 - mastermind like transcriptional coactivator 1 Gene

Also Known as Mam1; Mam-1; mKIAA0200; D930008C07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 103806

Summary

Enables transcription coactivator activity. Involved in atrioventricular node cell development and positive regulation of myotube differentiation. Acts upstream of or within myoblast differentiation and positive regulation of transcription of Notch receptor target. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb bud; and respiratory system epithelium. Orthologous to human MAML1 (mastermind like transcriptional coactivator 1). [provided by Alliance of Genome Resources, Apr 2022]

Maml1 Products (2)

mRNA Protein Name
NM_001401554.1 NP_001388483.1 mastermind-like protein 1 isoform 1
NM_175334.3 NP_780543.2 mastermind-like protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
15019995 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
15019995 MGI
involved in Notch signaling pathway IDA
IDA: Inferred from direct assay
15019995 MGI
involved in atrioventricular node cell development IMP
IMP: Inferred from mutant phenotype
21266778 MGI
involved in myoblast differentiation IEP
IEP: Inferred from expression pattern
16510869 MGI
involved in positive regulation of muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
16510869 MGI
involved in positive regulation of myotube differentiation IGI
IGI: Inferred from genetic interaction
16510869 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15019995 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15019995 MGI
acts upstream of or within positive regulation of transcription of Notch receptor target IGI
IGI: Inferred from genetic interaction
23160044 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
15019995 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mastermind-like protein 1

  • mastermind like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100431 IMR-1 Inhibitor 98.95% Unkown
HY-RS07999 MAML1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21639 Maml1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28157 Maml1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Maml1 NCBI NCBI:9794