Gldc - glycine decarboxylase Gene

Also Known as D19Wsu57e; b2b2679Clo; D030049L12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104174

Summary

Predicted to enable anion binding activity; glycine dehydrogenase (decarboxylating) activity; and protein homodimerization activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in mitochondrion. Is expressed in several structures, including integumental system; limb; nervous system; sensory organ; and urinary system. Used to study glycine encephalopathy. Human ortholog(s) of this gene implicated in glycine encephalopathy. Orthologous to human GLDC (glycine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Gldc Products (1)

mRNA Protein Name
NM_138595.2 NP_613061.1 glycine dehydrogenase (decarboxylating), mitochondrial precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine dehydrogenase (decarboxylating), mitochondrial

  • glycine cleavage system P protein

  • glycine dehydrogenase (aminomethyl-transferring)

  • glycine dehydrogenase [decarboxylating], mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05468 GLDC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20278 Gldc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26786 Gldc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gldc NCBI NCBI:2731