Cdk20 - cyclin-dependent kinase 20 Gene

Also Known as p42; CDCH; Ccrk; PNQLARE; 4932702G04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105278

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within several processes, including chordate embryonic development; embryonic organ development; and negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in thymus primordium. Orthologous to human CDK20 (cyclin dependent kinase 20). [provided by Alliance of Genome Resources, Apr 2022]

Cdk20 Products (1)

mRNA Protein Name
NM_053180.2 NP_444410.1 cyclin-dependent kinase 20

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20159594 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within embryonic brain development IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within embryonic camera-type eye development IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within embryonic skeletal system development IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within floor plate formation IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
28817564 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within protein localization to cilium IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within regulation of protein maturation IMP
IMP: Inferred from mutant phenotype
28817564 MGI
acts upstream of or within regulation of smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
28817564 MGI
acts upstream of or within roof of mouth development IMP
IMP: Inferred from mutant phenotype
28817564 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase 20

  • CAK-kinase p42

  • CDK-activating kinase p42

  • CDK-related protein kinase PNQLARE

  • cell cycle-related kinase

  • cell division protein kinase 20

  • cyclin-dependent protein kinase H

  • cyclin-kinase-activating kinase p42

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS28035 Cdk20 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk20 NCBI NCBI:23552