Abhd4 - abhydrolase domain containing 4 Gene

Also Known as Abh4; 1110035H23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105501

Summary

Enables lysophospholipase activity. Involved in N-acylphosphatidylethanolamine metabolic process. Acts upstream of or within N-acylethanolamine metabolic process. Predicted to be active in lipid droplet and mitochondrion. Is expressed in central nervous system; dorsal root ganglion; genitourinary system; and retina. Orthologous to human ABHD4 (abhydrolase domain containing 4, N-acyl Phospholipase B). [provided by Alliance of Genome Resources, Apr 2022]

Abhd4 Products (2)

mRNA Protein Name
NM_001205181.1 NP_001192110.1 (Lyso)-N-acylphosphatidylethanolamine lipase isoform 2
NM_134076.3 NP_598837.3 (Lyso)-N-acylphosphatidylethanolamine lipase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables lysophospholipase activity IDA
IDA: Inferred from direct assay
16818490 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within N-acylethanolamine metabolic process IDA
IDA: Inferred from direct assay
16818490 MGI
involved in N-acylphosphatidylethanolamine metabolic process IMP
IMP: Inferred from mutant phenotype
25853435 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

(Lyso)-N-acylphosphatidylethanolamine lipase

  • abhydrolase domain-containing protein 4

  • alpha/beta hydrolase domain-containing protein 4

  • alpha/beta-hydrolase 4

  • lyso-N-acylphosphatidylethanolamine lipase

  • protein ABHD4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164838 ABC47 Inhibitor 99.80% Unkown
HY-RS00095 ABHD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20845 Abhd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27359 Abhd4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abhd4 NCBI NCBI:63874