Adgrb1 - adhesion G protein-coupled receptor B1 Gene

Also Known as Bai1; mKIAA4089; B830018M07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 107831

Summary

Enables several functions, including PDZ domain binding activity; lipopolysaccharide binding activity; and phosphatidylserine binding activity. Involved in several processes, including negative regulation of protein metabolic process; phagocytosis; and positive regulation of myoblast fusion. Acts upstream of or within positive regulation of synapse assembly. Located in several cellular components, including focal adhesion; phagocytic cup; and postsynaptic density. Is expressed in several structures, including brain and reproductive system. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human ADGRB1 (adhesion G protein-coupled receptor B1). [provided by Alliance of Genome Resources, Apr 2022]

Adgrb1 Products (2)

mRNA Protein Name
NM_001359759.1 NP_001346688.1 adhesion G protein-coupled receptor B1 isoform 2
NM_174991.3 NP_778156.2 adhesion G protein-coupled receptor B1 isoform 1precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
23782696 MGI
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
21245295 MGI
enables phosphatidylserine binding IDA
IDA: Inferred from direct assay
17960134 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11245925 MGI
enables transmembrane signaling receptor activity IDA
IDA: Inferred from direct assay
17960134 MGI
Biological Process GO Annotation Evidence References Source
involved in defense response to Gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
21245295 MGI
involved in engulfment of apoptotic cell IDA
IDA: Inferred from direct assay
17960134 MGI
involved in negative regulation of protein catabolic process IMP
IMP: Inferred from mutant phenotype
25751059 MGI
involved in negative regulation of protein ubiquitination IMP
IMP: Inferred from mutant phenotype
25751059 MGI
involved in phagocytosis, engulfment IMP
IMP: Inferred from mutant phenotype
26838550 MGI
involved in phagocytosis, recognition IMP
IMP: Inferred from mutant phenotype
21245295 MGI
involved in positive regulation of myoblast fusion IMP
IMP: Inferred from mutant phenotype
23615608 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
involved in regulation of synaptic plasticity IMP
IMP: Inferred from mutant phenotype
25751059 MGI
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
20888903 MGI
located in focal adhesion IDA
IDA: Inferred from direct assay
20888903 MGI
located in phagocytic cup IDA
IDA: Inferred from direct assay
17960134 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
17960134 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
23595754 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor B1

  • brain-specific angiogenesis inhibitor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-131031 KCC-07 99.97% Unkown
HY-RS00345 ADGRB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19762 Adgrb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26259 Adgrb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrb1 NCBI NCBI:575