Grm2 - glutamate receptor, metabotropic 2 Gene
Also Known as Gprc1b; mGluR2; mGluR7; 4930441L02Rik
Species: Mus musculus
About Grm2
This gene has 4 transcripts (splice variants), 280 orthologues, 7 paralogues and is associated with 10 phenotypes. Biased expression in frontal lobe adult (RPKM 23.), cortex adult (RPKM 16.8) and 6 other tissues.
Summary
Enables Calcium Channel regulator activity and group II metabotropic glutamate receptor activity. Acts upstream of or within chemical synaptic transmission; gene expression; and glutamate homeostasis. Located in neuron projection. Is expressed in brain. Orthologous to human GRM2 (glutamate metabotropic receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
Grm2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001160353.1 | NP_001153825.1 | metabotropic glutamate receptor 2 precursor |
Grm2 Protein Structure
PBP1_mGluR_groupII: cd06375 (25 - 479)
NCD3G: pfam07562 (495 - 545)
7tmC_mGluR2: cd15447 (565 - 818)
7tmC_mGluR2: cd15447 (565 - 590)
7tmC_mGluR2: cd15447 (602 - 623)
7tmC_mGluR2: cd15447 (632 - 656)
7tmC_mGluR2: cd15447 (678 - 698)
7tmC_mGluR2: cd15447 (723 - 749)
7tmC_mGluR2: cd15447 (757 - 780)
7tmC_mGluR2: cd15447 (787 - 812)
- 0
- 200
- 400
- 600
- 800
- 872 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
metabotropic glutamate receptor 2 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS05822 | GRM2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05823 | Grm2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05824 | Grm2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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