1. Gene
  2. Grm3 - glutamate receptor, metabotropic 3 Gene

Grm3 - glutamate receptor, metabotropic 3 Gene

Mus musculus

Also known as mGlu3; Gprc1c; mGluR3; 0710001G23Rik

Gene ID: 108069 | Gene type: protein coding

About Grm3

Chromosome 5: 9,535,541-9,775,170 reverse strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 215 orthologues, 7 paralogues and is associated with 22 phenotypes. Biased expression in cortex adult (RPKM 11.5), frontal lobe adult (RPKM 9.3) and 4 other tissues.

Summary

Enables Calcium Channel regulator activity and group II metabotropic glutamate receptor activity. Acts upstream of or within gene expression. Located in several cellular components, including glutamatergic synapse; postsynaptic density; and synaptic membrane. Is integral component of postsynaptic membrane. Is integral component of presynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and visual system. Orthologous to human GRM3 (glutamate metabotropic receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Grm3 Products(1)

mRNA Protein Name
NM_181850.2 NP_862898.1 metabotropic glutamate receptor 3 precursor

Grm3 Protein Structure

PBP1_mGluR_groupII

PBP1_mGluR_groupII: cd06375 (32 - 493)

NCD3G

NCD3G: pfam07562 (504 - 554)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 599)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 827)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (611 - 632)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (641 - 665)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (687 - 707)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (732 - 758)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (766 - 789)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (796 - 821)

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  • 879 a.a.
Protein Preferred Names Protein Names

metabotropic glutamate receptor 3

G protein-coupled receptor, family C, group 1, member C

Orthologs Information

Species Symbol Source ID
Homo sapiens Grm3 NCBI NCBI:2913