TSPAN9 - tetraspanin 9 Gene

Also Known as NET5; NET-5; PP1057

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10867

About TSPAN9

Cytogenetic location: 12p13.33-p13.32 Genomic coordinates (GRCh38): 12:3,077,379-3,286,559 (from NCBI)

This gene has 9 transcripts (splice variants), 271 orthologues and 32 paralogues. Broad expression in heart (RPKM 31.5), placenta (RPKM 20.4) and 23 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]

TSPAN9 Products (2)

mRNA Protein Name
NM_001168320.2 NP_001161792.1 tetraspanin-9
NM_006675.5 NP_006666.1 tetraspanin-9

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
18795891 GOA
located in tetraspanin-enriched microdomain IDA
IDA: Inferred from direct assay
18795891 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPAN9 Protein Structure

Tetraspannin

Tetraspannin: Tetraspanin family (8 - 230)

  • 0
  • 100
  • 200
  • 239 a.a.
Protein Preferred Names Protein Names

tetraspanin-9

  • new EST tetraspan 5

Related Diseases

Diseases Alias
Fallopian Tube Carcinoma

  • Fallopian Tube Cancer

  • Cancer Of The Fallopian Tube

  • Carcinoma Of Fallopian Tube

  • Neoplasm Of Fallopian Tube

  • Fallopian Tube Neoplasms

  • Fallopian Tube Ca

  • Fallopian Tube Neoplasm

  • Malignant Neoplasm Of Uterine Tube

  • Malignant Tumor Of Fallopian Tube

  • Malignant Tumour Of Fallopian Tube

  • Tumor Of The Fallopian Tube

  • Tumor, Fallopian Tube, Malignant

  • Malignant Tumor Of Fallopian Tubes

  • Cancer Of Fallopian Tubes

  • Malignant Tubal Tumor

  • Tubal Cancer

  • Malignant Neoplasm Of Fallopian Tube

  • Primary Malignant Neoplasm Of Fallopian Tube

  • Cancer Of The Oviduct
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15175 TSPAN9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TSPAN9 VGNC VGNC:100115
Felis catus TSPAN9 VGNC VGNC:66637
Canis familiaris TSPAN9 VGNC VGNC:47926
Mus musculus TSPAN9 MGD MGI:1924558
Rattus norvegicus TSPAN9 RGD RGD:1304740
Bos taurus TSPAN9 VGNC VGNC:36443
Others TSPAN9 NCBI