BTG3 - BTG anti-proliferation factor 3 Gene

Also Known as ANA; TOB5; TOFA; APRO4; TOB55; ANA/BTG3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10950

About BTG3

Cytogenetic location: 21q21.1 Genomic coordinates (GRCh38): 21:17,593,653-17,612,901 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 181 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 24.4), placenta (RPKM 23.0) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

BTG3 Products (2)

mRNA Protein Name
NM_001130914.2 NP_001124386.1 protein BTG3 isoform a
NM_006806.5 NP_006797.3 protein BTG3 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17690688 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of mitotic cell cycle IDA
IDA: Inferred from direct assay
9632145 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9632145 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BTG3 Protein Structure

BTG

BTG: BTG family (1 - 117)

  • 0
  • 100
  • 200
  • 252 a.a.
Protein Preferred Names Protein Names

protein BTG3

  • B-cell translocation gene 3

Related Diseases

Diseases Alias
Cataract 37

  • CTRCT37

  • Cca5

  • Cataract, Congenital, Cerulean Type, 5

  • Cataract 37, Autosomal Dominant

  • Congenital Cataract Cerulean Type 5
Enterokinase Deficiency

  • Enteropeptidase Deficiency

  • Congenital Enterokinase Deficiency

  • Congenital Enteropathy Due To Enteropeptidase Deficiency

  • Deficiency Of Enteropeptidase

  • ENTKD
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01664 BTG3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta BTG3 VGNC VGNC:70289
Mus musculus BTG3 MGD MGI:109532
Rattus norvegicus BTG3 RGD RGD:2226
Bos taurus BTG3 VGNC VGNC:26599
Felis catus BTG3 VGNC VGNC:60205
Canis familiaris BTG3 VGNC VGNC:38559
Others BTG3 NCBI